201. Author: tailgater | Date: Tue, 6/16/2020, 9:07AM EST | |
teedubbya wrote:This came across my desk from the FDA today (EUA is Emergency Use Authorization)
On June 15, 2020, based on FDA’s continued review of the scientific evidence available for hydroxychloroquine sulfate (HCQ) and chloroquine phosphate (CQ) to treat COVID-19, FDA has determined that the statutory criteria for EUA as outlined in Section 564(c)(2) of the Food, Drug, and Cosmetic Act are no longer met. Specifically, FDA has determined that CQ and HCQ are unlikely to be effective in treating COVID-19 for the authorized uses in the EUA. Additionally, in light of ongoing serious cardiac adverse events and other serious side effects, the known and potential benefits of CQ and HCQ no longer outweigh the known and potential risks for the authorized use. This warrants revocation of the EUA for HCQ and CQ for the treatment of COVID-19.
I know not everyone understands how medical studies and peer reviewed journals operate and why some may be pulled because of extremely stringent data specifications while others might still be out there that do not self impose those standards. You have to recognize them for what they are and are not instead of the knee jerk political crap we tend to make everything in here.
It is looking more and more like this particular drug is not pat of the solution. Hopefully it turns around and becomes the miracle drug the politicians pushed and shows benefit but it is not promising at the moment. No politics, just facts. If it were a miracle drug, the tests would already point that out. I work indirectly with the FDA (my customers submit medical devices for their 510k and we get involved at the materials level quite frequently). I hate their glacial pace, but I trust their motives and therefore their decisions. For the most part. There was no harm in following up on the anecdotal evidence. But politics lead many to believe otherwise. |
202. Author: danmdevries | Date: Tue, 6/16/2020, 9:51AM EST | |
I was never on board. We used it, but i saw no benefit. However, nobody went without it, so there wasn't anything to compare. If it was a miracle drug, people would recover. We did not see that.
Now its plasma and remdesivir. Still not seeing anectodal positives. Some recover, as did with plaquenil and I suspect would have without. But we don't yet have established treatment beyond supportive as is the case with most viral infections. |
203. Author: DrafterX | Date: Tue, 6/16/2020, 10:42AM EST | |
I've been mainlining listerine and haven't caught the Rona yet.... I find the mint flavor to go a little easier than the regular stuff... |
204. Author: tonygraz | Date: Tue, 6/16/2020, 11:47AM EST | |
Better take an extra dose before you go to the upcoming trump rally. |
205. Author: frankj1 | Date: Tue, 6/16/2020, 4:30PM EST | |
so you agree tw is a deek?
ooops...for #200 |
206. Author: delta1 | Date: Tue, 6/16/2020, 6:00PM EST | |
appreciate insight from danm, as well as TW, and Spey...always good to hear from the frontlines... |
207. Author: tailgater | Date: Tue, 6/16/2020, 7:29PM EST | |
frankj1 wrote:so you agree tw is a deek?
ooops...for #200 Only 200 think TW is a deek? |
208. Author: tonygraz | Date: Tue, 6/16/2020, 8:54PM EST | |
Bragging because you have 423 ? |
209. Author: izonfire | Date: Wed, 6/17/2020, 5:40PM EST | |
frankj1 wrote:..................
I really have appreciated your brilliance, your patience in all of this, and mostly your struggle to fend off those trying to paint you into a political corner. What you do for a living is awesome, and to do it while going through your personal issues is off the charts amazing.
Thank you. The only time I find TW remotely palatable is when he doesn’t post. Which is rare. Yet, you talk about the man like he’s a selfless beacon for humanity. It’s almost like you’re preparing to defend him against future litigation. What has he done? What do you know?… |
210. Author: frankj1 | Date: Wed, 6/17/2020, 6:04PM EST | |
I plead the fifth. Then I'll drink it. |
211. Author: tailgater | Date: Wed, 6/17/2020, 8:37PM EST | |
tonygraz wrote:Bragging because you have 423 ? That's nothing to brag about. But it IS more than double. Just sayin. |
212. Author: victor809 | Date: Fri, 7/3/2020, 10:04AM EST | |
Hey! hydroxycholoquine is BACK ON AGAIN!
https://www.cnn.com/2020/07/02/health/hydroxychloroquine-coronavirus-detroit-study/index.html
So.... 13% mortality with HCQ, 20% mortality with HCQ+AZT and 26% mortality with neither.
Now this still is not a great study. They chose which patients got the HCQ +AZT... (ones without heart issues, so technically healthier patients....)that would be a BIG nono if you were trying to prove effectiveness of a drug in a designed study (this is just a review of data).
And, the most critical part.... the HCQ group apparently was also treated with steroids at a rate 2x that of the other groups. Since we've also seen a benefit from steroids in serious cases... this may be the artifact. |
213. Author: Speyside | Date: Fri, 7/3/2020, 10:11AM EST | |
Prolly has nothing to do with the facts you mentioned. The moron we call president says it works. That all you need to know. |
214. Author: victor809 | Date: Tue, 7/28/2020, 9:40AM EST | |
Hydroxychloroquine is BACK ON AGAIN!!! Today Trump and Trump Jr were singing the praises and retweeting information from Dr Stella Immanuel who has claimed that she has treated hundreds of patients with hydroxychloroquine and all of them survived.
She also claims that vaccines are designed to prevent people from being religious, that demons have sex with you in your sleep... and something about Alien DNA. So I'm sure she's a great source of information for this.
http://archive.is/G7wtb
|
215. Author: victor809 | Date: Tue, 7/28/2020, 9:43AM EST | |
.... and Hydroxychloroquine is OFF AGAIN!!!!
https://www.military.com/daily-news/2020/05/23/more-1300-veterans-given-hydroxychloroquine-covid-19.html
Looks like the VA has been using hydroxycholoquine on its patients. Those treated with HCQ have been dying at a rate of like 28%.... HCQ and AZT has a death rate of 22%... while treating with neither was at about 11%.
Almost like they're killing our veterans in an attempt to prove the president right. Ah well. I'm sure everyone's ok with that.
-caveat - I do not know if this study was blinded or whether patient selection for treatment was randomized or not. Maybe we should be believing the demon sperm anti-vaxx dr from the post above instead. |
216. Author: HockeyDad | Date: Tue, 7/28/2020, 4:57PM EST | |
I’m bored with this drug. It’s generic and made by a bunch of companies. No real money to be made there. The new experimental (expensive) is where the money’s at. |
217. Author: victor809 | Date: Tue, 7/28/2020, 5:23PM EST | |
HockeyDad wrote:I’m bored with this drug. It’s generic and made by a bunch of companies. No real money to be made there. The new experimental (expensive) is where the money’s at. I am too. But trump's not. Just today - the dumbest president wrote: They think it is extremely successful, the hydroxychloroquine, coupled with the zinc ... it's safe
|
218. Author: frankj1 | Date: Tue, 7/28/2020, 6:46PM EST | |
simply stunned that a world leader could extol a sham fund raising religion/medicine mixer. Stunned that I know anyone at all who would do it, actually.
I'm not saying he even believes in her, which makes it more insane.
He has abandoned the office.
Dare I ask if any soft supporters here of Trump have finally seen enough?
Any Mature Adult 2020 |
219. Author: fiddler898 | Date: Tue, 7/28/2020, 6:51PM EST | |
What did you think of the Trump-recruited Dr. dog & pony show today? Rod Serling, move over. |
220. Author: rfenst | Date: Wed, 7/29/2020, 6:06AM EST | |
frankj1 wrote:simply stunned that a world leader could extol a sham fund raising religion/medicine mixer. Stunned that I know anyone at all who would do it, actually.
I'm not saying he even believes in her, which makes it more insane.
He has abandoned the office.
Dare I ask if any soft supporters here of Trump have finally seen enough?
Any Mature Adult 2020 Nope. You haven't seen anything yet. Just wait until August when he'll accept his nomination and October (if he feels his reelection is at stake). |
221. Author: Speyside | Date: Wed, 7/29/2020, 6:41AM EST | |
Per say nothing he does anymore stuns me. I always expect the worst. Then I expect his cult members to believe and defend him. |
222. Author: rfenst | Date: Wed, 7/29/2020, 9:46AM EST | |
Speyside wrote:Per say nothing he does anymore stuns me. I always expect the worst.... - Me too. |
223. Author: victor809 | Date: Wed, 7/29/2020, 9:52AM EST | |
This morning twitler continued to heap praise on the demon sperm Dr, saying something to the effect of "I was very impressed with her".
I hope I never in my life say something stupid enough that Trump will say how impressed he is with me. |
224. Author: skillett | Date: Wed, 7/29/2020, 1:01PM EST | |
JUST REMEMBER TRUMP2020 our only hope for America. At least I won't vote for any thieves shackled down in Washington to steal from us for another 4 years.
Sure glad obummer and hillary got that pockets lined with lots of money, and even had the brashness to accept a paycheck. by the way, their two of satan's children. |
225. Author: victor809 | Date: Wed, 7/29/2020, 1:07PM EST | |
Whole lot crammed into that post.
Anyone want to come collect their grandfather? He's forgotten where the facebook was again.
Don't forget to take your hydroxychloroquine skillet... and don't let demons have any more sex with you. |
226. Author: delta1 | Date: Wed, 7/29/2020, 1:32PM EST | |
I hope the re-awakening for Trump supporters isn't too painful...we need a functioning two party system...not this hateful, divided place where our POTUS has convinced so many people to believe disinformation, lies and distortions...
who do you believe? me or your lyin eyes?
|
227. Author: rfenst | Date: Wed, 7/29/2020, 2:27PM EST | |
Kodak gets $765M loan from US to produce medicines, reportedly including hydroxychloroquine
Kodak has been given a $765 million loan from the federal government to produce drugs in the US, reportedly including hydroxychloroquine, the malaria medicine that President Donald Trump has been pushing as a COVID-19 treatment. Trump on Tuesday directed the US International Development Finance Corporation to sign a letter of interest to provide the loan under the Defense Production Act to Eastman Kodak Company to launch Kodak Pharmaceuticals.
Kodak will rely on its "vast infrastructure, deep expertise in chemicals manufacturing, and heritage of innovation and quality" in launching Kodak Pharmaceuticals, executive chair Jim Continenza said. "Kodak is proud to be a part of strengthening America's self-sufficiency in producing the key pharmaceutical ingredients we need to keep our citizens safe." |
228. Author: victor809 | Date: Wed, 7/29/2020, 2:36PM EST | |
Yeah, and mysteriously, on Monday there was an increase in trading activity for Kodak stock. Normally apparently 50-200k, but on Mon 1,650 shares traded hands.
Nothing suspicious about that. |
229. Author: rfenst | Date: Wed, 7/29/2020, 2:54PM EST | |
Yeah, the stock went up so much today that it triggered an automatic shut-down of the stock for a couple hours. |
230. Author: frankj1 | Date: Wed, 7/29/2020, 2:59PM EST | |
I have a Brownie camera somewhere. |
231. Author: rfenst | Date: Wed, 7/29/2020, 4:08PM EST | |
I remember the Instamatic and its film cartridges.
|
232. Author: Smooth light | Date: Wed, 7/29/2020, 7:21PM EST | |
Bring on the mighty Quinn so we can use are freedom to chose. Stop all this caudswhup in other words BS. So come on out and come on in,thier's nothing like the mighty Quinn and and we'll jump with joy for the MIGHTY QUINN!!!! |
233. Author: frankj1 | Date: Wed, 7/29/2020, 7:36PM EST | |
Smooth light wrote:Bring on the mighty Quinn so we can use are freedom to chose. Stop all this caudswhup in other words BS. So come on out and come on in,thier's nothing like the mighty Quinn and and we'll jump with joy for the MIGHTY QUINN!!!! Dylan, not Manfred Mann |
234. Author: tonygraz | Date: Wed, 7/29/2020, 8:27PM EST | |
frankj1 wrote:I have a Brownie camera somewhere. Racist ! |
235. Author: MACS | Date: Wed, 7/29/2020, 9:35PM EST | |
https://tinyurl.com/yy3szvp6
Well... that's interesting. Professor of epidemiology at Yale... has written over 300 peer reviewed publications... wrote an article for American Journal of Epidemiology stating ""Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis." |
236. Author: Speyside | Date: Mon, 8/3/2020, 8:20PM EST | |
That dumb SOB talked about it again today. Could he pleeeeeease move on to a different con job. BTW, the world death rate is .6%. This is 6 times greater than the flu. Oh, if anyone wants to say we don't know how many people have had COVID 19, I agree with that. We also do not know how many people have the flu each year. Also, the flu does not cause autoimmune disease, COVID19 does. |
237. Author: tonygraz | Date: Tue, 8/4/2020, 8:34AM EST | |
And he will continue to say it works because he is too crazy to ever admit that he was wrong. Never apologizes, has no pets and can't stop lying to try to make himself look good. |
238. Author: victor809 | Date: Tue, 8/4/2020, 10:12AM EST | |
MACS wrote:https://tinyurl.com/yy3szvp6
Well... that's interesting. Professor of epidemiology at Yale... has written over 300 peer reviewed publications... wrote an article for American Journal of Epidemiology stating ""Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis." Yeah, it appears he got ripped apart by a number of other epidemiologists in letters to the editor after that. Enough so that he then had to write his own letter to the editor trying to defend himself. I didn't read all the letters, but I read his defense. It boiled down to "non randomized studies are important too!" Randomized, double blinded studies. Without them, data always tends to look questionable. And actually is. People (all people) are notoriously bad at influencing results when they know what they want to achieve. |
239. Author: teedubbya | Date: Mon, 3/15/2021, 12:59PM EST | |
Good ol hydroxy |
240. Author: delta1 | Date: Mon, 3/15/2021, 1:17PM EST | |
didn't Trump get cured by hydroxychloroquine when he got the COVID?
wait...no...it was Regeneron's monoclonal antibody cocktail, experimental drug which very few people can get...dexamethasone and remdesivir |
241. Author: teedubbya | Date: Mon, 3/15/2021, 1:22PM EST | |
While I was working directly with hospitals trying to use Hydroxy and finding it didn't do what was suggested.... I was also doing the research into who says it does and who (non political) says it doesn't at the research level not paying attention to Trump, TDS or any of that other garbage.... legitimate studies old, new, and ongoing. I even shared the treatment protocols based on the same info.
at the same time, folks claiming others have TDS and are purposely not looking at hydroxy because of well... trump. It was opposite world. We were looking at everything. It's medicine. We were using hydroxy at the time. It is frustrating. The experts in here were bashing the actual experts and suggesting something that could not have been further from the truth. And the stupidity continues.
Now some idiot says I didn't share my sources/data when all he had to do is actually look at what I gave him. I did share. And it was all about hydroxy which is even more funny. Good god I can't share everything in detail. You MUST do your own work and thinking. You won't believe me anyway.
Hydroxy turned out to not be what the politicians said it was. My favorite is a thread where DMV suggests it has 60 years of study so it doesn't need more LMAO..... for treating covid. Really. This is how stupid it gets but people forget what they said. |
242. Author: teedubbya | Date: Mon, 3/15/2021, 1:44PM EST | |
By the way treatment protocols have come a long way. We are much better now. Politics don't treat people. Laymen don't treat people. |
243. Author: delta1 | Date: Mon, 3/15/2021, 4:19PM EST | |
experience can be a great teacher...
just don't want to be the "error" in "trial and error" |
244. Author: teedubbya | Date: Mon, 3/15/2021, 4:58PM EST | |
We have quickly gotten better at testing, treating, and preventing. It been fascinating to watch. Yea science. |
245. Author: Smooth light | Date: Mon, 3/15/2021, 6:39PM EST | |
'THE MIGHTY QUINN'...we told you so... nuthing good comes from blind hate. Science over Emotions!! 🧫 vs 🤬 |
246. Author: frankj1 | Date: Mon, 3/15/2021, 7:56PM EST | |
Smooth light wrote:'THE MIGHTY QUINN'...we told you so... nuthing good comes from blind hate. Science over Conservatives!! 🧫 vs 🤬 so true. Thank you Even Trump got vaccinated. He just wishes his worshippers didn't find out. |
247. Author: Smooth light | Date: Tue, 3/16/2021, 12:17PM EST | |
Your emotions are showing when you modify or edit the words of others. The whole world knows he was, even the fake news reported it.
Can't twist facts to fit your agenda. Facts are subject to change, the truth is subject only to time. We'll just have to see were the chips fall and deal with it. |
248. Author: RayR | Date: Tue, 3/16/2021, 12:38PM EST | |
Oh! Victor is back! Goody Goody!🥳 |
249. Author: frankj1 | Date: Tue, 3/16/2021, 12:39PM EST | |
Smooth light wrote:Your emotions are showing when you modify or edit the words of others. The whole world knows he was, even the fake news reported it.
Can't twist facts to fit your agenda. Facts are subject to change, the truth is subject only to time. We'll just have to see were the chips fall and deal with it. it's called humor, not an emotional breakdown. No one knew it at the time, you made that up. |
250. Author: HockeyDad | Date: Tue, 3/16/2021, 12:40PM EST | |
Get well soon Frank. |