Any duplicate "resistance" wired in parallel halves the resistance. Thus, 2 4-ohm speakers wired in parallel will give you 2-ohms that needs to be driven.
Wiring in series is additive. Thus, 2 4-ohm speakers give you 8-ohms.
Now here something to keep in mind: the wattage and resistance ratings for amplifiers and speakers are not simple resistance calculations, but take impeadance as a factor. Impeadance is a function of frequency. Much of this has to do with the speaker being seen by the circuitry as being a coil (inductance).
Furthermore, while you may have an amp that take a 1-ohm, 1600W load, what you're essentially doing by bogging down the amp is pushing the maximum amount of current out the back, possibly affecting the frequency response, and generating more heat on the driving transistors. The heat is the most crutial issue, as over time, heat will damage the power transistors that drive the speakers.
Most amplifier designs make the trade-off of frequency response for power. Having one that does both is rather rare. They also tend to get a little expensive. My opinion is that if you're looking to get a fairly long life out of the amp, draw less power from it.
Having 500W driving a speaker or two is a helluva lot of power.