It's an anti inflammatory medication that's fairly recently been added to the cardiovascular arsenal. There's an ongoing study with it right now.
Pericardial effusion is fluid build up within the sac around the heart. If there's too much incompressible fluid within the fibrous pericardium, it restricts motion of the heart.
Post-cardiotomy there's major local and systemic inflammatory response. Just as you get swelling when you bump your knee and stuff, same happens internally. Steroids are avoided in open heart because they also suppress rebuilding tissue at surgical sites while suppressing immune response. So recently we've been looking at other options for these situations and initial data on colchicine is positive.
danmdevries wrote: