The U.S. Food and Drug Administration (FDA) said on Wednesday a serious genital infection has been reported in patients taking a certain class of diabetes drugs, with one death and 11 others hospitalized.

The warning pertains to a class of medicines called SGLT2 inhibitors, first approved in 2013 to lower blood sugar in adults with type 2 diabetes.

The U.S. health regulator has also called for including this risk in the drugs’ labeling.


The SGLT2 inhibitors approved by the FDA include Johnson & Johnson’s Invokana, Eli Lilly & Co’s Jardiance, as well those from Bristol-Myers Squibb, Astra Zeneca Plc, Merck & Co and Pfizer Inc.

The companies did not immediately respond to Reuters request for comment.

Patients are at risk of the infection known as Fournier’s gangrene, an extremely rare but life-threatening bacterial infection of the tissue under the skin that surrounds the genital area, the FDA said in a statement.

The bacteria usually enter the body through a cut and quickly spread. Having diabetes is a risk factor for developing Fournier’s gangrene.


One patient died, while some required multiple disfiguring surgeries and developed complications, the agency said.

The infection developed within several months of the patients starting an SGLT2 inhibitor and the drug was stopped in most cases, the FDA said.

Film at 11.... 😟

you got the sugar?

Sorry to hear about your genital infections drafter....


Does Hallmark make a card for this?

Not me man... [-(


But I bet some here do....

My taint itches when I eat a Snickers. Related?

Possibly, I guess that depends on how many Snickers you eat.

good to know...thanks for the heads up, Drafter...luckily for me I don't need the inhibitors ... yet ...

20-30 a day.

You want serious Genital Infections don't you... 😟

hmmmmmm...how often do you shower, Jade?

fun size or the big guys?

..... There's a joke there....

I know, just couldn't come up with it though so I tossed it underhand to the crowd.

"drafter or Frank"?

"mini or Giant Pounder"?

Youin's catch the ZAG-NUT disease DRAFTER?
Or just...
Snow Cap Rectumitis?

"minnow or giant flounder"?

Jade told me the "BIG GUYS" are the "FUN SIZE"...8-[

Fournier’s gangrene is one of the more disgusting things I deal with at work.

And Jade is going to get that from gobbling the big guy Snickers?