Eh..............the short answer is yes..........in can be a problem...........even in the same fiver, or box, etc.
I'm having that problem right now with some Oliva V samplers I got over a year ago..............so far at least one in each sampler has tasted like an ashtray..........in one of the samplers, 3 out of 5 were like that!
It's not my storage, blah blah.....................Internet cigars!