No, I haven't. We don't leave the city often (read 3x in the past year)... Last weekend was the first time we went to Old Town where we weren't under a tight timeline.
Heck, we just figured out the metro goes all the way out to old-town. 🙂
We don't have a car, just take the metro or walk or taxi where we want to go. So we usually stay within a 15 block radius of our place for nightlife. That gets us to most hot-spots.