HockeyDad
5 years ago
The Pfizer COVID-19 vaccine is significantly less effective against the delta variant than the Moderna vaccine, according to a new preprint study from the Mayo Clinic that has yet to be peer-reviewed.

Both vaccines are still highly effective against severe disease from the delta variant COVID-19, the study authors stressed. However, Moderna was found to be, on average, 76% effective against infection from the delta variant compared to Pfizer, which was 42% effective against infection from the variant.

"The elephant in the room is the amount of mRNA in the vaccines," said Venky Soundarajan, the cofounder and chief scientist at Nference, the data analytics arm of the Mayo Clinic based in Cambrdige, Massachusetts.

The Moderna vaccine has a greater amount of mRNA than the Pfizer vaccine, Soundarajan said, which may account for the differences in protection against the delta variant.

Soundarajan also noted that the nanoparticulation and nucleotide sequences used in the vaccines are different, but the prevailing hypothesis is that Moderna is more effective against the variant due to the greater amount of mRNA in the vaccine.

The Moderna vaccine, especially the second shot, is associated with a greater increase in mild side effects compared to Pfizer, Soundarajan added.

"Thinking back, we think that might be because of the dose," he said. "There is more mRNA, which means it boosts a stronger immune response."

The study, which is undergoing peer review (a process that typically takes two to three months), looked at over 75,000 people in the Mayo Clinic system. The Mayo Clinic is based in Minnesota.

There are some "caveats" to the study, Soundarajan said. For one, genome sequencing is limited, so the study authors estimated the number of suspected delta variant cases using inferred data. In other words, those studied were not necessarily infected with the delta variant, but were suspected as being so as it is the prevailing variant in the U.S. right now.

The study authors are also unsure whether the lower effectiveness of the Pfizer vaccine is due to its status as the first vaccine to receive FDA emergency-use authorization. Because Pfizer's vaccine was the first approved, it was rolled out to communities with higher risks of contracting serious side effects from the coronavirus, Soundarajan said. Health care workers and elderly people living in care facilities received the vaccine first, for example, and the data may be inflected by this fact.
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RayR
5 years ago
You know...This whole experimental vaccine thing is nuts and not very scientific.

This is Nuts, Moderna and Pfizer Intentionally Lost The Clinical Trial Control Group Testing Vaccine Efficacy and Safety

August 6, 2021 | Sundance

This is not just scientific madness, it appears to be very intentional and purposeful.

The Moderna and Pfizer vaccine tests were conducted, as customary, with a control group; a group within the trial who were given a placebo and not the test vaccine. However, during the trial -and after the untested vaccines were given emergency use authorization- the vaccine companies conducting the trial decided to break protocol and notify the control group they were not vaccinated. Almost all the control group were then given the vaccine.

Purposefully dissolving the placebo group violates the scientific purpose to test whether the vaccine has any efficacy; any actual benefit and/or safety issues. Without a control group there is nothing to compare the vaccinated group against. According to NPR, the doctors lost the control group in the Johnson County Clinicial Trial (Lexena, Kansas) on purpose:

More...

https://theconservativetreehouse.com/blog/2021/08/06/this-is-nuts-moderna-and-pfizer-intentionally-lost-the-clinical-trial-control-group-testing-vaccine-efficacy-and-safety/ 



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HockeyDad
5 years ago
What the **** is a conservative tree house?
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RayR
5 years ago

What the **** is a conservative tree house?

HockeyDad wrote:



It's a thing man! A blog thing where they make fools out of leftist progtards and stuff.


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drglnc
5 years ago

What the **** is a conservative tree house?

HockeyDad wrote:




the site has been Patient Zero for a number of hoaxes that have percolated through right-wing media ecosystem, claiming that Puerto Rican truck drivers were withholding hurricane relief, or that a top official at the Centers for Disease Control and Prevention was “weaponizing” the coronavirus to hurt Trump. Despite those hoaxes being quickly debunked, however, The Conservative Treehouse now ranks at roughly the 4,000th most-visited website in the United States, according to Alexa analytics.

Its zeal for the conspiratorial is so pronounced that even some of Donald Trump’s staunchest allies in right-wing media find the site’s devoted commenters and its pseudonymous operator, “Sundance,” bizarre. Talk radio host Mark Levin has called it a “kook site.” Former Breitbart reporter Lee Stranahan dubbed the site’s owner an “egocentric lunatic” with “cult-like followers.”

Treehouse owner “Sundance” is just another Q... maybe even the same idiot with a different name... finding other idiots to share the nonsense... every once in a while they sprinkle in just enough "fact" to almost be believed by some...
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gummy jones
5 years ago
I think I'm happy with the Pfizer shot

Severe disease is really all I care about
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MACS
5 years ago
You seen the drug commercials on TV?

You see all the side effects and disclaimers they legally have to spout during each?

Yeah... those are drugs and shots and stuff that have gone through the years of testing, reviews, and red tape to get FDA approved.

These mRNA shots are still emergency use only approved... right? And the "clinical trials" part is ongoing, right?

Just asking.
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Krazeehorse
5 years ago
Looks like Pfizer might be the better investment. But you don’t really know in the long run.
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zitotczito
5 years ago

Looks like Pfizer might be the better investment. But you don’t really know in the long run.

Krazeehorse wrote:



I owned PFizer stock and made a nice profit when I sold yesterday at $48.00. I now have to consider if I want to get back in. I am really not sure.
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RayR
5 years ago

the site has been Patient Zero for a number of hoaxes that have percolated through right-wing media ecosystem, claiming that Puerto Rican truck drivers were withholding hurricane relief, or that a top official at the Centers for Disease Control and Prevention was “weaponizing” the coronavirus to hurt Trump. Despite those hoaxes being quickly debunked, however, The Conservative Treehouse now ranks at roughly the 4,000th most-visited website in the United States, according to Alexa analytics.

Its zeal for the conspiratorial is so pronounced that even some of Donald Trump’s staunchest allies in right-wing media find the site’s devoted commenters and its pseudonymous operator, “Sundance,” bizarre. Talk radio host Mark Levin has called it a “kook site.” Former Breitbart reporter Lee Stranahan dubbed the site’s owner an “egocentric lunatic” with “cult-like followers.”

Treehouse owner “Sundance” th a different is just another Q... maybe even the same idiot winame... finding other idiots to share the nonsense... every once in a while they sprinkle in just enough "fact" to almost be believed by some...

drglnc wrote:



Maybe you didn't read the article in your zeal to trash talk the site...it's based on information directly reported and linked to NPR.

I don't know...if the neocon Mark Levin and Lee Stranahan, the guy has been all over, currently employed by Sputnik News and did formerly work for Breitbart but has written for such far-left crazies as The Huffington Post and Daily Kos and has even been a pornographer, if those two bad mouth that blog, there must be some value there.
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ZRX1200
5 years ago
Conservative Tree House is where we hide all of the Dave’s Killer bread from all the kookoo birds.
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HockeyDad
5 years ago

I owned PFizer stock and made a nice profit when I sold yesterday at $48.00. I now have to consider if I want to get back in. I am really not sure.

zitotczito wrote:



How can you people be talking about buying a stock when people are dying from COVID-19?

(Put me down for 500 shares)
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Mr. Jones
5 years ago
Fu*k me in the arse!!!!

I chose the Pfizer...

Moderna was not a choice...

Only Pfizer and Johnson...

F*ck me in dee arse!!!


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Mr. Jones
5 years ago
SHHHHEEEEEEETTTTTT....

I was fff***ccckkkEeeD***
Wit a lesser producTttt to the varianttt
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drglnc
5 years ago

Maybe you didn't read the article in your zeal to trash talk the site...it's based on information directly reported and linked to NPR.

I don't know...if the neocon Mark Levin and Lee Stranahan, the guy has been all over, currently employed by Sputnik News and did formerly work for Breitbart but has written for such far-left crazies as The Huffington Post and Daily Kos and has even been a pornographer, if those two bad mouth that blog, there must be some value there.

RayR wrote:




Oh, i read the article, as well as the original NPR article it references. Hence my sprinkling of facts comment in my post... one relatively accurate article or blog doesn't change or negate what i said about the treehouse as a whole... its a wack job magnet in line with the Qtards and pillow man bs...
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Burner02
5 years ago

How can you people be talking about buying a stock when people are dying from COVID-19?

(Put me down for 500 shares)

HockeyDad wrote:




You may want to double up, boosters coming in the very near future.
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delta1
5 years ago
we're still talking about rigid testing requirements for the vaccines more than 9 months after mass inoculation????

with very few adverse side effects and clear proof of efficacy in the real world among the 1.25 BILLION fully vaccinated people??????


the days when we needed the results of the clinical studies passed in December when the infection, hospitalization and death rates from COVID were through the roof, and most honest people said let's stop testing the fire hose, it works well enough...this house is on fire and we're burning up...
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HockeyDad
5 years ago

we're still talking about rigid testing requirements for the vaccines more than 9 months after mass inoculation????

with very few adverse side effects and clear proof of efficacy in the real world among the 1.25 BILLION fully vaccinated people??????


the days when we needed the results of the clinical studies passed in December when the infection, hospitalization and death rates from COVID were through the roof, and most honest people said let's stop testing the fire hose, it works well enough...this house is on fire and we're burning up...

delta1 wrote:



No. We’re talking about something different. Confusion is a side effect of Covid-19. You should get tested.
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delta1
5 years ago
ooops...conservative tree house...my bad
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